教員

中根 孝久教授 / 博士(薬学)last update : 2023.12.22

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研究者名
中根 孝久(ナカネ タカヒサ)
所属
生薬?天然物化学研究室
担当科目
基礎生物学2(1年後期)
薬系公定書概論(2年後期)
生薬学2(3年前期)
機器分析学(3年前期)
天然物化学(3年後期)
生薬?天然物化学実習(3年後期)
漢方治療学(4年後期)
職位
教授
学位
博士(薬学)

所属学協会

日本薬学会

日本生薬学会

日本アロマセラピー学会

  • 原著論文 Three Minor Flavone Glycosides from Aeschynanthus Species and Cultivars (Gesneriaceae) T. Iwashina, S. Rahayu, T. Nakane, T.i Mizuno, C. Tsutsumi, and D. Widyatmoko Natural Product Communications 18(8) 1-4 2023 
  • 原著論文 Ecological and pharmacognostical characteristics in Ephedra saxatilis in the Yarlung Zangbo River Valley of southeastern Tibetan Plateau, China M. Minami, Y. Honda, K. Ueno, T. Matsunaka, J. Wang, L. Zhu, A. Takano, T. Nakane Journal of Natural Medicines 77 614-619 2023 
  • 原著論文 Anthocyanin and Flavones from the Flowers of Tripora divaricata (Lamiaceae) and their Contribution to Blue Violet Color T. Mizuno, H. Seto, T. Nakane, Y. Murai, F. Tatsuzawa and T. Iwashina Bull. Natl. Mus. Nat. Sci., Ser. B 49(2) 57-64 2023 
  • 原著論文 Flavonoids from the leaves and stems of Rhodiola ishidae (Crassulaceae) T. Iwashina, T. Nakane, H. P. Devkota Biochemical Systematics and Ecology 107 104622 2023 
  • 原著論文 Impallidane skeleton as a novel triterpenoid methyl ether from rhizomes of Imperata cylindrica var. koenigii f. pallida. Y. Sakai, J. Shinozaki, A. Takano, T. Nakane Journal of Natural Medicines 77 379-386 2023 
  • 原著論文 Flavonoids from the leaves of Amorphophallus asper and Amorphophallus paeoniifolius (Araceae) T. Iwashina, S. Rahayu, D. K. Sugahara, T. Nakane, T. Mizuno, C. Tsutsumi, D. Widyatmoko Phytochemistry Letters 53 132-136 2023 
  • 原著論文 Ephedra equisetina の栽培研究(I) 中野 美央,井櫻 晶,中根 孝久,川端 良子,Jollibekov Berdiyar,Ivan Ivanovich Maltsev,高野 昭人 日本植物園協会誌 第57号 14-24 2023 
  • 原著論文 A novel screening method for ingredients of essential oil to identify antibacterial compounds based on growth curve shape Y. Inoue, T. Nakane, Y. Arai Journal of Pharmacognosy and Phytochemistry 11(4) 273-276 2022 
  • 原著論文 Flavonoids from Sedum japonicum subsp. oryzifolium (Crassulaceae) T. Mizuno, N. Uchiyama, S. Tanaka, T. Nakane, H. P. Devkota, K. Fujikawa, N. Kawahara and T. Iwashina Molecules 27(21) 7632 2022 
  • 原著論文 Flavonoid glycosides from Hylotelephium sieboldii var. sieboldii and var. ettyuense endemic to Japan  T. Iwashina, M. Nakata, T. Nakane, T. Mizuno Biochemical Systematics and Ecology 105 104505 2022 
  • 原著論文 Flavonoids and phenylethanoids from the flowers and leaves of Aeschynanthus species and cultivars (Gesneriaceae) T. Iwashina, S. Rahayu, T. Nakane, H. P. Devkota, T. Mizuno, C. Tsutsumi, D. Widyatmoko Phytochemistry 203 113367 2022 
  • 原著論文 Relationship between ephedrine alkaloid profile in Ephedra gerardiana and soil characteristics of glacial landforms in southeastern Tibetan Plateau, China M. Minami, T. Mori, Y. Honda, K. Ueno, T. Murakami, T. Matsunaka, J. Wang, L. Zhu, A. Takano, T. Nakane Journal of Natural Medicines 76 703-714 2022 
  • 原著論文 Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein (YAP) degrader N. Nakano, K. Fukuda, E. Tashiro, H. Ishikawa, W. Nagano, R.e Kawamoto, A. Mori, M. Watanabe, R. Yamazaki, T. Nakane, M. Naito, I. Okamoto, S. Itoh The Journal of Biochemistry 171(6) 631-640 2022 
  • 原著論文 lavonoids and Phenolic Compounds From the Parasitic Gymnosperm Parasitaxus usta Endemic to New Caledonia T. Iwashina, H. Tobe, T. Nakane, T. Mizuno and T. Jaffré Natural Product Communications 17(1) 1-6 2022 
  • 原著論文 Narciclasine is a novel YAP inhibitor that disturbs interaction between YAP and TEAD4 R. Kawamoto, N. Nakano, H. Ishikawa, E. Tashiro, W. Nagano, K. Sano, M. Irie, M. Ikuta, F. Kishi, T. Nakane, M. Naito, S. Itoh BBA Advances 1 100008 2021 
  • 原著論文 Two triterpene synthases from Imperata cylindrica catalyzing the formation of a pair of diastereoisomers through boat or chair cyclization S. Naraki, M. Kakihara, S. Kato, Y. Saga, K. Mannen, S. Takase, A. Takano, S. Shinpo, T. Hosouchi, T. Nakane, H. Suzuki, T. Kushiro ChemBioChem 22(11) 1992-2001 2021 
  • 原著論文 Dopamine modulation of chemotactic behavior in response to natural aroma substances in Drosophila melanogaster larvae T. Shibuya, T. Nakane, A. Takano, J. Yamauchi, T. Morimoto Phytomedicine Plus 1 100007 2021 
  • 原著論文 Environmental and soil characteristics in Ephedra habitats of Uzbekistan M. Minami, T. Fujii, Y. Honda, K. Ueno, J. Shinozaki, S. Itoh, A. Takano, J. Berdiyar, I. I. Maltsev, T. Nakane Journal of Natural Medicines 75(1) 246-258 2020 
  • 原著論文 Physical and chemical characteristics of soils in Ephedra gerardiana and E. pachyclada habitats of Kali Gandaki Valley in Central Nepal M. Minami, T. Mori, Y. Honda, K. Ueno, T. Murakami, Yui Ajioka, T.i Atsumi, K. J. Joshi, P. M. Yadav, D. R. Kandel, M. Nakano, J. Shinozaki, S. Itoh, T. Nakane, A. Takano Journal of Natural Medicines 74 825-833 2020 
  • 原著論文 ウズベキスタンに自生する Ephedra 属植物に関する現地調査 高野昭人,篠崎純一,中根孝久,三宅克典,南基泰,Jollibekov Berdiyar,川端良子,Maltsev Ivan Ivanovich 薬用植物研究 41(1) 23-30 2019 
  • 原著論文 Four new triterpenoids from the bark of Euonymus alatus forma ciliato-dentatus H. Yamashita, M. Matsuzaki, Y. Kurokawa, T. Nakane, M. Goto, K.-H. Lee, T. Shibata, H. Bando, K. Wada Phytochemistry Letters 31 140-146 2019 
  • 原著論文 Germination and morphological features of bluestem joint fir (Ephedra equisetina) seeds under different LED light conditions Berdiyar JOLLIBEKOV, J.-a. CHE, T. HUANG, S. KAGAMI, A. TAKANO, T. NAKANE, M. YAMADA, Y. KAWABATA, I. OGIWARA Journal of Arid Land Studies 28-S 101-104 2018 
  • 原著論文 Quality Testing of Tacrolimus Ointment Mixed with Various Type of Ointments or Creams T. Nakane, H. Doi, M. Hirohara, H. Hamashima, and Y. Inoue Biol. Pharm. Bull. 41(11) 1632-1637 2018 
  • 原著論文 Three novel 14-epiarborane triterpenoids from Imperata cylindrica Beauv. Y. Sakai, J. Shinozakia, A. Takanoa, K. Masudaa, T. Nakane Phytochemistry Letters 26 74-77 2018 
  • 原著論文 ネパール?Tistung Botanical Garden での薬用植物栽培試験 高野昭人,中根孝久,伊東進,Kuber Jung Malla,Gopal Karki 日本植物園協会誌 第52号 103-107 2017 
  • 原著論文 Distribution of Eight Vitamin E Homologs Found in 81 Plants Using LC-MS3 T. Inoue, S. Honma, Y. Otsuka, T. Nakane, A. Takano, Y. Gamo, F. Hashidume, H. Yuasa, Y. Nakanishi and Y. Hirahara J Nutr Food Sci 2017 7(6) 1000636 2017 
  • 原著論文 ネパール?イラム地方マイポカリ地域における薬用植物 Swertia chirayita の栽培に関する現地調査 高野昭人,中根孝久,Paras Mani YADEV,Dhana Raj KADEL,Kuber Jung Malla,Yam Bhahadur THAPA,伊東進 日本植物園協会誌 第50号 55-56 2015 
  • 原著論文 Acyl flavonoids, biflavones, and flavonoids from Cephalotaxus harringtonia var. nana N. Komoto, T. Nakane, S. Matsumoto, S. Hashimoto, O. Shirota, S. Sekita, M. Kuroyanagi J. of Natural Medicine 69 479-486 2015 
  • 原著論文 A New Bis-seco-abietane Diterpenoid from Hyptis crenata Pohl ex Benth Y-S. Yun, H. Fukaya, T. Nakane, A. Takano, S. Takahashi, Y. Takahashi, H. Inoue org. Lett. 16(23) 6188-6191 2014 
  • 原著論文 Squalene Cyclases and Cycloartenol Synthases from Polystichum polyblepharum and Six Allied Ferns J. Shinozaki, T. Nakene and A. Takano Molecules 23(8) 1843 2013 
  • 原著論文 ベトナム?カッティエン国立公園での薬物資源調査 高野昭人,中根孝久,中野未央,石澤祐介,白子智康,味岡ゆい,南基泰,磯田進,矢原正治,山田祐彰,Do Tan Hoa,Tran Van Thanh 日本植物園協会誌 第47号 75-83 2013 
  • 原著論文 Water-Soluble Undenatured Type II Collagen Ameliorates Collagen-Induced Arthritis in Mice O. Yoshinari, Y. Shiojima, H. Moriyama, J. Shinozaki, T. Nakane, K. Masuda, M. Bagchi Journal of Medicinal Food 16(11) 1039-1045 2013 
  • 原著論文 Officinatrione: an unusual (17S)-17,18-seco-lupane skeleton, and four novel lupane-type triterpenoids from the roots of Taraxacum officinale D. Saeki, T. Yamada, Y. In, T. Kajimoto, R. Tanaka, Y. Iizuka, T. Nakane, A. Takano, K. Masuda Tetrahedron 69 1583-1589 2013 
  • 原著論文 The Identification of Vitamin E Homologues in Medicinal Plant Samples Using ESI (+) - LC-MS3 T. Inoue, S. Tatemori, N. Muranaka, Y. Hirahara, S. Homma, T. Nakane, A. Takano, Y. Nomi, Y. Otsuka Journal of agricultural and food chemistry 60(38) 9581-9588 2012 
  • 原著論文 Leishmanicidal Active Withanolides from a Pakistani Medicinal Plant, Withania coagulans M. Kuroyanagi, M. Murata, T. Nakane, O. Shirota, S. Sekita, H. Fuchino, Z. K. Shinwari Chem. Pharm. Bull. 60(7) 892-897 2012 
  • 原著論文 Transannular Cyclization of (4S,5S)-Germacrone-4,5-epoxide into Guaiane and Secoguaiane-type Sesquiterpenes M. Kuroyanagi, O. Shirota, S. Sekita, T. Nakane Natural Product Communications 7(4) 441-446 2012 
  • 原著論文 Composite Constituent: Lactucenyl Acetate, a Novel Migrated Lupane Triterpenoid from Lactuca indica Revision of Structure of Tarolupenyl Acetate J. Shinozaki, T. Nakane, N. Onodera, A. Takano, K. Masuda Chem. Pharm. Bull. 59(6) 767-769 2011 
  • 原著論文 Ursolic acid and oleanolic acid, members of pentacyclic triterpenoid acids, suppress TNF-alpha-induced E-selectin expression by cultured umbilical vein endothelial cells.  K. Takada, T. Nakane, K. Masuda, H. Ishii Phytomedicine 17 1114-1119 2010 
  • 原著論文 Production of sesquiterpene-type phytoalexins by hairy roots of Hyoscyamus albus co-treated with cupper sulfate and methyl jasmonate M. Kawauchi, T. Arima, O. Shirota, S. Sekita, T. Nakane, Y. Takase, M. Kuroyanagi Chem. Pharm. Bull. 58(7) 939-938 2010 
  • 原著論文 Polyprenylated benzoylphloroglucinol-type derivatives including novel cage compounds from Hypericum erectum.  Y. Ishida, O. Shirota, S. Sekita, K. Someya, F. Tokita, T. Nakane, M. Kuroyanagi Chem. Pharm. Bull. 58(3) 336-343 2010 
  • 原著論文 Metabolome analysis of Ephedra plants with different contents of ephedrine alkaloids by using UPLC-Q-TOF-MS. T. Okada, Y. Nakamura, S. Kanaya, A. Takano, J. K. Malla, T. Nakane, M. Kitayama, S. Sekita Planta Medica 75(12) 1356-1362 2009 
  • 原著論文 Screening of Nepalese crud drugs traditionally used to treat hyperpigmentation: in vitro tyrosinase inhibition. A. Adhikari, H. P. Devkota, A. Takano, K. Masuda, T. Nakane, P. Basnet, N. Skalko-Basnet Journal of Cosmetic Science 30(5) 353-360 2008 
  • 原著論文 Rearranged lanostane triterpenoids from Abies sachalinensis (III). H. Y. Gao, L. J. Wu, T. Nakane, O. Shirota, M. Kuroyanagi Chem. Pharm. Bull. 56(9) 1352-1354 2008 
  • 原著論文 Beyerane derivatives and a sesquiterpene dimer from Japanese cypress (Chamaecyparis obtusa).  H. Y. Gao, L. J Wu, N. Muto, H. Fuchino, T. Nakane, O. Shirota, T. Sano, M. Kuroyanagi, Chem. Pharm. Bull. 56(7) 1030-1034 2008 
  • 原著論文 Novel lanostane and rearranged lanostane-type triterpenoids from Abies sachalinensis.  H. Y. Gao, L. J. Wu, T. Nakane, O. Shirota, M. Kuroyanagi Chem. Pharm. Bull. 56(4) 554-558 2008 
  • 原著論文 Triterpene glycosides from the roots of Codonopsis lanceolata. M. Ushijima, N. Komoto, Y. Sugizono, I. Mizuno, M. Sumihiro, M. Ichikawa, M. Hayama, N. Kawahara, T. Nakane, O. Shirota, S. Sekita, M. Kuroyanagi Chem. Pharm. Bull. 56(3) 308-314 2008 
  • 原著論文 Neurite outgrowth-promoting active constituents of the japanese cypress (Chamaecyparis obtusa).  M. Kuroyanagi, R. Ikeda, H. Y. Gao, N. Muto, K. Otaki, T. Sano, N. Kawahara, T. Nakane Chem. Pharm. Bull. 56(1) 60-63 2008 
  • 原著論文 Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.  N. Murayama, N. Imai, T. Nakane, M. Shimizu, H. Yamazaki Biochemical Pharmacology 73(12) 2020-2026 2007 
  • 原著論文 New Diarylheptanoids from Alnus japonicum and Their Antioxidative Activity M. Kuroyanagi, m. Shimome, Y. Nagashima, N. Muto, T. Okuda, N. Kawahara, T. Nakane, T. Sano Chem. Pharm. Bull. 53(12) 1519-1523 2005 
  • 原著論文 Biotransformation of Benzaldehyde-type and Acetophenone-type Derivatives by Pharbitis nil Hairy Roots. H. Kanho, S. Yaoya, N. Kawahara, T. Nakane, Y. Takase, K. Masuda, M. Kuroyanagi Chem. Pharm. Bull. 53(4) 361-365 2005 
  • 原著論文 Glucosylation of Phenolic Compounds by Pharbitis nil Hairy Roots: I. Glucosylatyion of Coumarin and Flavone Derivatives. H. Kanho, S. Yaoya, T. Itani, T. Nakane, N. Kawahara, Y. Takase, K. Masuda, M. Kuroyanagi Bioscience Biotechnology and Biochemistry 68(10) 2032-2039 2004 
  • 原著論文 テンモンドウの TLC による確認試験について 渕野裕之,中根孝久,高橋真理衣,関田節子 Natural Medicines 57(1) 27-30 2003 
  • 原著論文 Antitumor-Promoting Constituents from Chaenomeles sinensis KOEHNE and Their Activites in JB6 Mouse Epidermal Cells H. Gao, L. Wu, M. Kuroyanagi, K. Harada, N. Kawahara, T. Nakane, K. Umehara, A. Hirasawa, Y. Nakamura Chem. Pharm. Bull. 51(11) 1318-1321 2003 
  • 原著論文 Study on Aquatic Fern: Terpenoids of Azolla japonica. T. Nakane, T. Matsuhisa, Y. Arai, K. Masuda, A. Takano, K. Shiojima Journal of Natural Medicines 57(5) 201 2003 
  • 原著論文 Bacopasides III-V: Three New Triterpenoids Glycosides from Bacopa monniera A. Kumar Chakaravarty, S. Garai, K. Masuda, T. Nakane, N. Kawahara Chem. Pharm. Bull. 51(2) 215-217 2003 
  •  New Phenylethanoid Glycosides from Bacopa monniera A. K. Chakravarty, T. Sarkar , T. Nakane, N. Kawahara , K. Masuda Chem. Pharm. Bull. 50(12) 1616-1618 2002 
  • 原著論文 Fern Constituents: Triterpenoids from Adiantum capillus-veneris T. Nakane, Y. Maeda, H. Ebihara, Y. Arai, K. Masuda, A. Takano, H. Ageta , K. Shiojima, Shao-Qing CAi, O. B. Abdel-Halim Chem. Pharm. Bull. 50(9) 1273-1275 2002 
  • 原著論文 Bacopaside I and II: two new pseudojujubogenin glycosides from Bacopa monniera A. K. Chakravarty, T. Sarkar, K. Masuda, K. Shiojima, T. Nakane, N. Kawahara Phytochemistry 58 553-556 2001 
  • 原著論文 Establishment of NIHS baicalin reference standard, H. Saito, M. Iwata, K. Maekawa, T. Tanimoto, S. Okada, H. Kamakura, N. Kawahara, T. Nakane, S. Sekita, M. Satake, Y. Yokota, T. Tsuno, H. Suzuki, K. Iwashima, K. Matsuura Iyakuhin Kenky 31(7) 465-470 2000 
  • 原著論文 Chemotaxonomy of Ferns: Triterpenoids and rbcL gene Sequences of Polypodium, Polypodiodes and Goniophlebium. M. Hirohara, T. Nakane, Y. Terayama, A. Kobayashi, Y. Arai, K. Masuda, H. Hamashima, K. Shiojima, H. Ageta Journal of Natural Medicines 54(6) 330-333 2000 
  • 原著論文 Fern Constituents: Six New Triterpenoid Alcohols from Adiantum capillus-veneris T. Nakane, Y. Arai, K. Masuda, Y. Ishizuka, H. Ageta, K. Shiojima Chem. Pharm. Bull. 47(4) 543–547 1999 
  • 原著論文 Fern Constituents: Adiantum cuneatum. III. Four New Triterpenoids, 4,23-Bisnor-3,4-secofilic-5(24)-en-3-al, 4,23-Bisnor-3,3-dimethoxy-3,4-secofilic-5(24)-ene, 7β,25-Epoxyfern-9(11)-en-8α-ol and 7α,8α-Epoxyfernan-25-ol K. Shiojima, Y. Arai, T. Nakane, H. Ageta, Shao-Qing Cai Chem. Pharm. Bull. 45(10) 1608-1610 1997 
  • 原著論文 Fern Constituents: Adiantum cuneatum. II. Six New Triterpenoids, Neohop-18-en-12α-ol, 13-Epineohop-18-en-12α-ol, Neohop-13(18)-en-19α-ol, Fern-7-en-25-ol, Fern-9(11)-en-25-ol and Adian-5-en-25-ol. K. Shiojima, Y. Arai, T. Nakane, H. Ageta Chem. & Pharm. Bull. 45(4) 639-642 1997 
  • 原著論文 Fern Constituents: Adiantum cuneatum. I. Three New Triterpenoids, Glaucanol B Acetate, 7β,25-Epoxyfern-8-ene and 25-Norfern-7-en-10β-yl Formate. K. Shiojima, Y. Arai, T. Nakane, H. Ageta Chem. & Pharm. Bull. 45(4) 636-638 1997 
  • 原著論文 Fern Constituents: Two New Secofilicane Triterpenoids from Adiantum cuneatum K. Shiojima, T. Nakane, H. Ageta, Shao-Qing Cai Chem. Pharm. Bull. 44(3) 630-632 1996 

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